所在院系：生命科学学院

申报人：陈军

适应性渐渗为生物快速适应环境变化提供了大量关键性遗传变异。本研究中通过聚焦两种同域生长的栎属植物麻栎和栓皮栎，揭示了影响渐渗发生的主要因子及其如何帮助植物快速适应环境变化的遗传机制。我们的研究结果显示物种间分化程度越弱或生长环境越相似，越大概率在相同的基因组位置发生渐渗。适应性渐渗更大概率发生在由TEs插入形成的顺式调控元件中，并响应外界环境信号刺激。基因组结构性变异，如染色体倒位能通过自然选择将适应性渐渗位点以“超基因”的形式聚集在染色体内。

Adaptive introgression is one of the most critical sources of genetic variation for adaptation to environmental changes. In this study, we focused on two sympatric oak species Quercus acutissima and Q. variabilis to reveal the genetic mechanisms underlying introgression and how it contributes to adaptation under quickly changing environments. Our results show that introgression can be determined by both genetic and environmental similarity, which means two species tend to exchange genes at the same genomic regions if they diverged at the same pace from a recent ancestral and live in similar environmental conditions. Mutations of adaptive introgression are most likely located in cis-regulatory elements formed by TEs and can respond to environmental signals. Genomic structural variations such as chromosomal inversion induced by TE insert played an important role in the maintenance of adaptive introgression at “supergene” level with the help of natural selection.

实验团队

处理样本数据

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主要结果图

说明：

1）适应性渐滲在麻栎染色体内的分布规律，以及它们同自然环境因子间的关联性

2）栎属适应性进化机制的解释示意图：相似环境下两种栎属植物遗传物质的交换更容易发生在相同基因组区域，而这些区域因为发生了染色体结构变异而被自然选择保留下来，通过特殊的转座子插入响应外界环境刺激而改变基因表达水平

Ruirui Fu, Yuxiang Zhu, Ying Liu, Yu Feng, Rui-Sen Lu, Yao Li, Pan Li, Antoine Kremer, Martin Lascoux, Jun Chen*. Genome-wide analyses of introgression between two sympatric Asian oak species. Nature Ecology &Evolution, 6, 924-935.